Description

Buy Welireg For Sale In USA

What is Welireg?

Welireg (belzutifan) is used in the treatment of von Hippel-Lindau (VHL) disease to help reduce the size of tumors, including tumors in the brain and spinal cord called central nervous system hemangioblastomas, pancreatic neuroendocrine tumors, and renal cell carcinomas. Welireg is also used to treat advanced renal cell carcinoma (RCC) in certain adults. Buy Welireg For Sale In USA

Von Hippel-Lindau (VHL) disease is a rare genetic disorder that causes cysts, benign tumors, and malignant tumors to grow in the body due to a mutation in the Von Hippel–Lindau tumor suppressor gene. This change in the gene causes an accumulation in the protein HIF-2a, which is associated with tumor growth.

Welireg is a hypoxia-inducible factor (HIF) inhibitor that works by blocking HIF-2a, to help reduce tumor growth.

Welireg is manufactured for Merck Sharp & Dohme Corp.

What is Welireg used for?

Welireg received FDA approval on August 13, 2021, to treat adult patients with von Hippel-Lindau (VHL) disease who do not require immediate surgery but require therapy for central nervous system (CNS) hemangioblastomas, pancreatic neuroendocrine tumors (pNET), or renal cell carcinoma (RCC). Welireg is manufactured for Merck Sharp & Dohme Corp.

On December 14,2023, Welireg received FDA approval for the treatment of adult patients with advanced renal cell carcinoma (RCC) following a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor and a vascular endothelial growth factor tyrosine kinase inhibitor (VEGF-TKI). Buy Welireg For Sale In USA

Welireg side effects

Common Welireg side effects when taken for VHL disease may include lower hemoglobin, headache, dizziness, tiredness, nausea, increased blood sugar (increased thirst or urination, dry mouth, fruity breath), or abnormal kidney function tests.

Common Welireg side effects when taken for advanced RCC may include decreased hemoglobin, tiredness, muscle, and joint pain, changes in laboratory readings, increased creatinine, decreased lymphocytes, increased alanine aminotransferase, decreased sodium, increased potassium, and increased aspartate aminotransferase.

Serious Welireg side effects 

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have:

• low red blood cells (anemia) – pale skin, tiredness, feeling light-headed or short of breath, cold hands and feet; or
• low oxygen levels – shortness of breath, chest pain, fast heartbeats; or
• vision problems

Welireg may also cause the serious side effects of pneumonia, hemorrhage, and pleural effusion, sepsis and hemorrhage.