Description

Buy Trikafta For Sale In USA

What is Trikafta?

Trikafta is an oral combination medication that contains elexacaftor, ivacaftor, and tezacaftor, which may be used to treat adults and children aged 2 years and older with cystic fibrosis who have at least one copy of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene or another mutation that is responsive to treatment with Trikafta. Buy Trikafta For Sale In USA

Cystic fibrosis (CF) is caused by mutations in the CF gene, which causes a specific protein, called the cystic fibrosis transmembrane conductance regulator (CFTR) protein to not work the way it should. Fewer CFTR proteins get to the cell surface and, if they do reach the cell surface, do not open the way they should, which prevents the proper movements of chloride ions in and out of the cell. As a result, thick sticky mucus builds up in the organs, including the lungs.

The three ingredients in Trikafta work together to improve the functioning of the CFTR protein:

• Elexacaftor and tezacaftor help more CFTR proteins reach the surface
• Ivacaftor helps the CFTR proteins stay open for longer at the cell surface, allowing more chloride ions to flow through, which thins the mucus.

Before you take this medicine, you may need an FDA-approved CF mutation test to make sure you have either the F508del mutation or at least one other eligible mutation. Buy Trikafta For Sale In USA

Trikafta was first FDA-approved on October 21, 2019.

Warnings

Avoid in people with a known hypersensitivity to Trikafta or one of its components. Angioedema and anaphylaxis have been reported.

Use of Trikafta should be avoided in people with pre-existing advanced liver disease, (such as cirrhosis, portal hypertension, ascites, hepatic encephalopathy) unless the benefits outweigh the risks, as cases of liver failure leading to transplantation have been reported. Your healthcare provider will monitor your liver function throughout treatment.

Cataracts have been reported in pediatric patients treated with medications containing ivacaftor. Baseline and follow-up eye examinations should be conducted in children.

Trikafta may affect the way other medicines work, and other medicines may affect how Trikafta works. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Buy Trikafta For Sale In USA

It is not known if Trikafta is safe and effective in children under 2 years of age.