Description

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What is Jemperli?

Jemperli is a prescription medicine used for the treatment of mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) endometrial cancer, and dMMR solid tumors. Buy Jemperli For Sale In USA

Jemperli belongs to the class of drugs called programmed death receptor-1 (PD-1)–blocking antibodies. In healthy T-cells, PD-1 acts as a brake that prevents the cells from creating an out-of-control immune response, but in tumors, PD-1 can make T-cells inactive preventing them from killing cancer cells.

Jemperli works in the treatment of dMMR/MSI-H endometrial cancer and dMMR solid tumors by binding to the PD-1 receptor on T-cells to block the interaction with the PD-1 ligands PD-L1 and PD-L2, allowing the T-cells to activate and to attack and kill the cancer cells. Buy Jemperli For Sale In USA

What is Jemperli used to treat?

Jemperli is used to treat mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) endometrial cancer, and dMMR solid tumors.

Endometrial cancer is a cancer that forms in the endometrium (lining of the uterus). Solid tumors are abnormal masses of tissue devoid of fluids or cysts. In normal cells, mismatch repair (MMR) is a process that corrects errors introduced during DNA replication via enzymes. When the repair mechanism is defective, it is known as mismatch repair-deficient (dMMR), and may lead to an accumulation of errors in the DNA that can cause cancer. Microsatellite instability (MSI) is the condition that results from impaired MMR. MSI-high (MSI-H) means that there is a high amount of instability in a tumor.

Jemperli is used in combination with the chemotherapy medicines carboplatin and paclitaxel, followed by Jemperli as a single agent for the treatment of adult patients with primary advanced (has spread outside the uterus) or recurrent (has returned) endometrial cancer that is mismatch repair deficient (dMMR), as determined by an FDA-approved test, or microsatellite instability-high (MSI-H). Buy Jemperli For Sale In USA

Jemperli is used as a single agent for the treatment of adult patients with dMMR recurrent or advanced endometrial cancer, as determined by an FDA-approved test, that has progressed during treatment or after treatment, and there are no satisfactory treatment options.

Jemperli is also as a single agent for the treatment of adult patients with dMMR recurrent or advanced solid tumors, as determined by an FDA-approved test, that have progressed during treatment or after treatment, and there are no satisfactory treatment options. Jemperli For Sale Online

It is not known if Jemperli is safe and effective in children.