Description

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What is Ayvakit?

Ayvakit is a prescription medicine used to treat adults with certain types of gastrointestinal stromal tumor (GIST) and systemic mastocytosis (SM).Ayvakit contains a drug called avapritinib, which belongs to the class of medicines called tyrosine kinase inhibitors. Buy Ayvakit For Sale In USA

GIST is a cancer of the gastrointestinal tract most often caused by mutations in the platelet-derived growth factor receptor alpha (PDGFRA) protein, which is part of a family of proteins called receptor tyrosine kinases (RTKs). Avapritinib works to treat GIST harboring a PDGFRA exon 18 mutation, including PDGFRA D842V mutations, by specifically targeting the mutant PDGFRA.

Systemic mastocytosis is a disorder characterized by the build up of mast cells in the body. It is most often caused by a D816V mutation in the KIT gene. Avapritinib works to treat advanced systemic mastocytosis (AdvSM) and indolent systemic mastocytosis (ISM) by specifically targeting KIT D816V.

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What is Ayvakit used to treat?

Ayvakit is used to treat gastrointestinal stromal tumor (GIST) that cannot be treated with surgery or is metastatic (has spread to other parts of the body), and that is caused by certain abnormal platelet-derived growth factor receptor alpha (PDGFRA) genes.

Your healthcare provider will perform a test to make sure that you have this abnormal PDGFRA gene and to ensure that Ayvakit is right for you.

Ayvakit is used to treat advanced systemic mastocytosis (AdvSM), including aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL).

Ayvakit is also used to treat indolent systemic mastocytosis (ISM).

It is not known if this medicine is safe and effective in children.

Before taking Ayvakit

Before you start treatment, tell your healthcare provider about all of your medical conditions. Buy Buy Ayvakit For Sale In USA

Pregnancy

Tell your healthcare provider if you are pregnant or plan to become pregnant. Ayvakit can cause harm to your unborn baby.

Females who are able to become pregnant:

• Your healthcare provider should do a pregnancy test before you start treatment.
•  You should use effective birth control (contraception) during treatment, and for 6 weeks after the final dose. Talk to your healthcare provider about birth control methods that may be right for you.
•  Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment.

Males with female partners who are able to become pregnant should use effective birth control (contraception) during treatment, and for 6 weeks after the final dose.