Description

Buy Verzenio (Abemaciclib) For Sale USA

Abemaciclib (brand name Verzenio) is used to treat HR+, HER2– early and metastatic breast cancer in women and men.

Abemaciclib’s mechanism of action involves blocking proteins involved in cell division called cyclin-dependent kinases (CDK), specifically CDK 4 and 6. Blocking these prevents cancer cells from dividing and multiplying uncontrollably because HR+ breast cancer cells rely heavily on CDK 4/6 for growth. Abemaciclib belongs to the drug class called CDK 4/6 inhibitors.

Abemaciclib is a targeted treatment, not chemotherapy (see Is Verzenio (abemaciclib) a chemo drug? for more information).

Abemaciclib uses

Abemaciclib is used to treat various types of hormone receptor-positive (HR+), human epidermal growth factor receptor 2 negative (HER2–) breast cancer. Specifically, abemaciclib is used in combination with:

• Endocrine therapy (tamoxifen or an aromatase inhibitor) to treat HR+, HER2– node-positive, early breast cancer that has a high risk of coming back
• An aromatase inhibitor (such as anastrozole, exemestane, or letrozole) as the first endocrine-based therapy to treat HR+, HER2– breast cancer that has worsened or spread (metastasized)
• Fulvestrant to treat HR+, HER2– breast cancer that has worsened or metastasized, and whose disease has progressed after endocrine therapy.

Abemaciclib is also used alone to treat HR+, HER2– breast cancer that has worsened or metastasized, and whose disease has progressed after endocrine therapy and prior chemotherapy.

When abemaciclib is used in combination with fulvestrant, tamoxifen, or an aromatase inhibitor, also read the Patient Medication Guide for those medicines. Ask your healthcare provider if you are not sure.

Abemaciclib side effects

The most common side effects of abemaciclib are:

• nausea
• infections
• low red blood cell counts (anemia)
• decreased appetite
• headache
• hair thinning or hair loss (alopecia)
• abdominal pain
• tiredness
• low white blood cell counts (leukopenia)
• vomiting
• low platelet count (thrombocytopenia)

Abemaciclib may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider if this is a concern for you.

Serious side effects and warnings

Get emergency medical help if you have signs of an allergic reaction to abemaciclib: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Abemaciclib may cause the following serious side effects.

Diarrhea. Diarrhea is common with abemaciclib and may sometimes be severe. Diarrhea may cause you to develop dehydration or an infection. The most common time to develop diarrhea is during the first month of abemaciclib treatment. If you develop diarrhea during treatment with abemaciclib, your healthcare provider may tell you to temporarily stop taking abemaciclib, stop your treatment, or decrease your dose.

If you have any loose stools, start taking an antidiarrheal medicine (such as loperamide), drink more fluids, and tell your healthcare provider right away.

Low white blood cell counts (neutropenia). Low white blood cell counts are common during treatment with abemaciclib and may cause serious infections that can lead to death. Your healthcare provider should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with abemaciclib, your healthcare provider may tell you to temporarily stop taking abemaciclib, decrease your dose, or wait before starting your next month of treatment. Tell your healthcare provider right away if you have signs and symptoms of low white blood cell counts or infections, such as fever and chills. Buy Verzenio (Abemaciclib) For Sale USA

Lung problems. Abemaciclib may cause severe or life-threatening inflammation of the lungs during treatment that can lead to death. If you develop lung problems during treatment with abemaciclib, your healthcare provider may tell you to temporarily stop taking abemaciclib, decrease your dose, or stop your treatment. Tell your healthcare provider right away if you have any new or worsening symptoms, including:

• trouble breathing or shortness of breath
• cough with or without mucus
• chest pain.

Liver problems. Abemaciclib can cause serious liver problems. Your healthcare provider should do blood tests to check your liver before and during treatment with abemaciclib. If you develop liver problems during treatment with abemaciclib, your healthcare provider may reduce your dose or stop your treatment. Tell your healthcare provider right away if you have any of the following signs and symptoms of liver problems:

• feeling very tired
• pain on the upper right side of your stomach area (abdomen)
• loss of appetite
• bleeding or bruising more easily than normal.